R Research using several mice. Mice. were given acetic acid solution for one month. With. investigating changes in the height and width of the rat tongue papillae, the measurement results of the administration of 10% acetic acid solution showed an average height of the tongue papillae = 18.52 µm and an average width of the tongue papillae 4.5 µm, the measurement results of the administration of 20% acetic acid solution showed an average height of the tongue papillae = 22.31 µm and an average width of the tongue papillae 7.12 µm, the measurement results of the administration of 30% acetic acid solution showed an average height of the tongue papillae = 20.7 µm and an average width of the tongue papillae 5.02 µm While the study was conducted on control mice with the administration of distilled water, the average height of the tongue papillae was 18.19 µm and the average width of the tongue papillae 4.68 µm. These results indicate that there has been no change.